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Weak immune system?

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Relliving-The-Past

PostPosted: Thu Aug 10, 2006 11:17 am


I've been looking lately at a friend with a weak immune system who's constantly sick because of it, and i've been looking a little more as a civilian to solve this. My question is this, Is there an way to transplant someone elts's T-Cells or Antibodies to another person without causing damage,but helping the other get stronger?
PostPosted: Thu Aug 10, 2006 3:01 pm


Probably not.

But there is a way to improve your immune system, and that is by getting sick more often and exposing yourself to more stuff.

Often times, also, if you have a weak immune system, your body will "dump" it and grow another one.

But this is kind of rare.

Oni no Tenshi
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Sylphi

PostPosted: Thu Aug 10, 2006 4:44 pm


The quickest and most effective method of transfering antibodies from one person to another that I know of is through nursing--i.e. breastmilk.

It seems sensible that it would also work on non babies.

Beyond that, I think you would really have to ask a doctor. You can't just, you know, get a bunch of blood and separate out the T cells and stick them in someone else.
PostPosted: Sat Aug 12, 2006 3:39 am


For the Lazy:
Quote:
So, no, you cannot just transplant someone's T-cells / antibodies into another person without causing damage.


For the Interested:

The immune system is activated by ANTIGENS - these are small protein molecules displayed by all cellular structures. These protein strings are unique to individuals, be it bacterial cells or human cells. For example, my antigenic protein string is slightly different from Oni's, who's is slightly different from Sylphi's and so on.

T cells and B cells are both major classes of lymphocytes - a type of white blood cell found in the human blood stream. T cells are critical immne system cells that help co-ordinate overall immune response (T-helper cells) or assist in destroying infected cells (T-killer cells). Both types of T cells have a molecule on the surface called the T-cell receptor, which interacts with MHC molecules. The MHC molecules - basically - hold out the antigen protein fragments for T-cells to bind and check for recognisation.

---

There are five main antibody types:
  • IgM
  • IgA
  • IgD
  • IgG
  • IgE

As Sylphi mentioned, some antibodies can transfer between persons via colostrum (breastmilk). This is (if I can remember correctly) the IgG antibody... which really isn't much good for adult immune response, but is enough to kickstart immune response in babies. IgG is also the only antibody which can bind to specialised receptors on placental cells for foetal circulation.

The major antibodies are IgM and IgA, as these are best for agglutination and creating large surface area molecules around the foreign cell (bacteria, maybe). IgE is also good at agglutination, however has the problematic effect of causing histamine release. Some of you IPG members might know this better as an allergic response. This is because IgE is important in parasite immunity - dust mites, etcetera.

---

Now, that's the explanation on basic immunology concepts. There's more, but it's unimportant to the question at hand.

If individuals display unique protein arrangement strings from the MHC molecule on cell surfaces, T-cells will recognise which is a good cell and which is a foreign cell. That's how it works for normal infection.

Reversing this, the donor's T-cells will not recognise the recipient's protein strings on the MHC molecule and will induce antibody response. This will invariably lead to Auto-Immune Disease, where the body attacks one's own organs and cells. It's the biggest hurdle that we face in terms of organ transplants, currently.

So, no, you cannot just transplant someone's T-cells / antibodies into another person without causing damage.

Tailos-teichou


Son of Axeman

PostPosted: Thu Aug 31, 2006 6:27 am


Thank you, Tailos, for that long-winded and confusing speech. My tired brain is now much.

Sylphi
The quickest and most effective method of transfering antibodies from one person to another that I know of is through nursing--i.e. breastmilk.

It seems sensible that it would also work on non babies.



That only works for 6 months after birth. There's a reason those wacky doctors urge your kids to get their vaccinations.
PostPosted: Thu Aug 31, 2006 7:32 am


Son of Axeman
Thank you, Tailos, for that long-winded and confusing speech. My tired brain is now much.


That's why I put the short version in a quote at the top. You didn't have to read it. ;]

Tailos-teichou


Random NaySayer

PostPosted: Tue Oct 03, 2006 9:13 pm


Sylphi
The quickest and most effective method of transfering antibodies from one person to another that I know of is through nursing--i.e. breastmilk.

It seems sensible that it would also work on non babies.

Beyond that, I think you would really have to ask a doctor. You can't just, you know, get a bunch of blood and separate out the T cells and stick them in someone else.


I heard that goat's milk is better for you thatn cow's milk is. It tastes worse, but it's much closer to human breast-milk.
PostPosted: Wed Oct 04, 2006 4:32 am


Random NaySayer
I heard that goat's milk is better for you thatn cow's milk is. It tastes worse, but it's much closer to human breast-milk.


There's a few arguments over this, but no solid proof of whether that's true. The main thing of switching to goat milk instead of cows milk is about calcium intake -- cow milk contains huge numbers of hormones that we really haven't studied enough, especially on the effects on humans.

So cow milk is supposedly a bad source of calcium and may actually be linked to osteoporosis as the calcium is in a different form than humans need it to be in.

Again, there's no real proof at all, however, besides a statistical link that suggests it. Could simply be coincidence.

Tailos-teichou


CrimsonDan

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PostPosted: Wed Oct 04, 2006 6:56 pm


that means the persons lmyphnodes(don't know if i spelled right) are not producing enough white blood cells. tell the person to get lots of vitamin c
PostPosted: Thu Oct 05, 2006 4:46 am


dwarfshorty
that means the persons lmyphnodes(don't know if i spelled right) are not producing enough white blood cells. tell the person to get lots of vitamin c


Yes and no.

It doesn't mean that the lymph nodes aren't producing enough white blood cells; it could be simply that they're not at high enough levels via vitamin C regulation.

Yes, you're right in that lots of vitamin C will certainly help things. :]

Tailos-teichou

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