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Table 2.
CHIR99021 and ECG parameters.
ECG Parameter Normal BP (n = 232) Prehypertension (n = 236) Stage 1 HT (n = 92) Stage 2 HT or anti-hypertensive medication (n = 111)
Odds ratio (95% CI) unadjusted Odds ratio (95% CI) adjusted age, smoking, waist Odds ratio (95% CI) unadjusted Odds ratio (95% CI) adjusted age, smoking, waist Odds ratio (95% CI) unadjusted Odds ratio (95% CI) adjusted age, smoking, waist Odds ratio (95% CI) unadjusted Odds ratio (95% CI) adjusted age, smoking, waist
Abnormal T axis (%) 1.00 1.00 1.09 (0.69–1.71) 1.08 (0.68–1.71) 0.94 (0.51–1.75) 0.95 (0.51–1.80) 1.34 (0.78–2.30) 1.38 (0.77–2.46)
Abnormal frontal QRS–T angle (%) 1.00 1.00 1.15 (0.38–3.46) 1.14 (0.37–3.47) 1.26 (0.31–5.14) 1.40 (0.33–5.90) 1.42 (0.39–5.15) 1.26 (0.29–5.47)
Major repolarization abnormalities (%) 1.00 1.00 1.39 diabetes mellitus (0.67–2.91) 1.37 (0.61–2.91) 0.77 (0.24–2.41) 0.75 (0.23–2.42) 1.67 (0.71–3.93) 1.62 (0.64–4.10)
Minor repolarization abnormalities (%) 1.00 1.00 1.21 (0.82–1.7 cool 1.25 (0.84–1.86) 1.10 (0.65–1.84) 1.17 (0.69–1.99) 1.18 (0.73–1.91) 1.33 (0.79–2.23)