2139
-- Saren Arterius is born.
-- Kahlee Sanders is born.

2141
-- Kar'Hallarn is born on the Kemorya.

-- Construction of Gagarin Station (Jump Zero) begins beyond the orbit of Pluto.

2144
-- Aella Tullius is born on Rocam.

2146
-- Thane Krios is born.

2147
-- Caecilius is born on Mars.

-- Trace amounts of element zero are discovered on Mars.

2148 - Humanity discovers Mass Effect physics

2149
-- Humans discover that Charon is a Mass Relay covered in ice.

2150
-- The Systems Alliance survey team discovers Terra Nova.
-- Miranda Lawson is born.

2151
-- The Systems Alliance begins constructing a military fleet and space station at Arcturus.
-- The accident at the Singapore International Spaceport exposes hundreds to dust-form element zero.
-- Kaidan Alenko is born.

2152
-- Humans begin settling on Demeter and Terra Nova.

2154
-- The second publicized accident resulting in exposure to element zero occurs.
-- April 11th: Shepard is born.

2155
-- The Systems Alliance moves in to completed portions of Arcturus Station.
-- Saren Arterius is promoted to active service in the turian military at the age of 16.
-- Jeff "Joker" Moreau is born.

2156
-- Arcturus Station is formally inaugurated.
-- Some human children exposed to element zero begin to show telekinetic ability.

2157 - The First Contact War begins
-- Aella leaves for boot camp 2 months after the Relay 314 Incident begins.

-- David Anderson graduates from Officer Candidate School with the rank of Second Lieutenant.
-- Jacob Taylor is born.

2158
-- Aella completes boot camp and applies to Citadel Security.

-- Humans learn about the potential of biotics.
-- April 14th: Ashley Williams is born.

2159
-- Saren Arterius becomes the youngest turian to be inducted into the Spectres.
-- The Systems Alliance purchases Gagarin Station, and converts the facility into a biotic research and training facility.

2160
-- Kar leaves the Migrant Fleet on his Pilgramage and arrives on Omega two months later.
-- Caecilius is found to have biotic ability and is shipped off to BAaT.

-- The Systems Alliance Parliament is formed.
-- The Biotic Acclimation and Temperance Training (BAaT) program is set up on Gagarin Station to train potential candidates and develop biotic implants. It is shut down in 2168.
-- The human biotic drug red sand is first used.
-- The Blue Suns mercenary group is founded by Zaeed Massani and Vido Santiago in the Skyllian Verge.

2161
-- Aella completes her training with C-Sec and joins the main force.

-- The Systems Alliance Parliament passes the Sudham-Wolcott Genetic Heritage Act. It imposes sharp restrictions on controversial uses of genetic engineering, but provides government subsidies for beneficial applications.
-- Tali'Zorah nar Rayya is born.
-- Jack is born.

2162
-- Aella is promoted to a position on the Presidium.
-- Kar starts seeing turian dreadnought parts coming in as salvage.

-- Construction of Arcturus Station is completed.
-- A survey team working for batarian entrepreneur Edan Had'dah discovers a mysterious artifact orbiting an unnamed planet near the Perseus Veil.

2163
-- Kar has finally collected enough money, and travels to the Citadel.
-- Caecilius undergoes surgery to have an experimental biotic amplifer implanted. As a result of a complication during the procedure, he is rendered blind

-- The Alliance secretly begins illegal AI research at a base on Sidon with Dr. Shu Qian as project leader. Lt. Kahlee Sanders is assigned as a tech analyst.
-- The first experimental L1 biotic implants are used in humans.
-- A series of starship drive failures are orchestrated over populated areas on human colony worlds.
-- The Leviathan of Dis, a genetically-engineered living starship believed to be nearly a billion years old, is discovered by a batarian survey team on the planet Jartar.

2164
-- Kar meets Aella
-- Due to a teleporter malfunction, Tayce is sent nearly 600 years into the past.
-- Caecilius and Tayce meet.
-- Caecilius and Tayce move to the Citadel and have 5 children.

-- Ivor Johnstagg is sentenced to 21 years in prison for attempting to assassinate Venta Tox, the volus ambassador to the Citadel.

2165 - Humanity is granted an embassy on the Citadel

-
-
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2183 - The events of Mass Effect begin



TLN Characters at 2164:
-Caecilius is 17 years old.
-Tayce is 19 years old.
-Aella is 20 years old.
-Kar is 23 years old.

Important people in relation to 2164:
-6 years have passed since the Relay 314 Incident


-Tali is 3 years old
-Jack is 3 years old
-Kasumi is 4 years old
-Ashley is 6 years old
-Jacob is 7 years old
-Joker is 9 years old
-'Shepard' is 10 years old
-Kaiden is 13 years old
-Miranda is 14 years old
-Thane is 18 years old
-Saren is 25 years old
-Liara is 87 years old

Source: Mass Effect Timeline on the Mass Effect Wikia page.