Adam (Sam and Dean's half-brother) is coming back again, back from the dead, not entirely sure why as yet, we just know he's returning.
Also, apparently we're going to need to queue up
this song for the episode in two weeks and making angsty fanvids with it - despite it not being an angsty song.
Even Angels Fall?
Castiel?
If we've worked it out right, this is an episode with Anna returning.
And from what she and Misha said at Collectormania, I know those two have a 'break up' of sorts in this episode.
So Cas may be forced to kill her.
Or our beloved Cas could be falling, or at least a nice big angsty scene where he's admitting to Dean that he's losing his powers and he's afraid.
I want that SO bad, it's not even from a shippery point of view, I just want Cas to admit weakness.
(Gone off on a tangent here, this ISN'T a spoiler, this is just what I want).