For the most part, a lot of stuff comes with practice. One thing that I did personally though (It actually came to me in a dream!) is find out if your oekaki has layers-- if it does, sketch out a vague outline on layer 0, then zoom in 2 times and on layer 1 draw your lineart over the sketch. Zooming in allows you a LOT more control and detail work.
When you're done with the lineart, go back to layer 0 and erase the sketch. Color on layer 1 turning on mask-- it basically lets you color without going over the black outline you created (I think it only works if your outlines are black though)
Since you did the whole picture on layer 1, you have layer 0 to do a background that won't interfere with the rest of the picture.
Wheela! I hope that helps. heart