I have an idea, subject to your approval. How about we use a 'mad science' kind of villain group? I was thinking of I.O. from Gen 13, since DC bought those characters from Wildstorm. I.O. is a 'shadow government' working behind the scenes of the U.S. Government. They are attempting to create (again) superpowered agents under their control:
http://dc.wikia.com/wiki/International_OperationsI.O. is similar to N.O.W.H.E.R.E. in scope and power. Thinking further, we could use either organization or an amalgam of the two to throw at the Titans. With the Titans 'broken up', IO may take an opportunity to snag up different metahuman teens for their experiments. I've used the IO plot in another guild and oddly enough, IO went after the Titans.
Tell me what you all think.