
This laboratory is built into the side of a small island located in a large body of water. It is first seen when Orochimaru brings Kabuto to the building to explain the reason he was attacked by Nonō and how it was part of a plan engineered by Danzō. Orochimaru then explains to Kabuto that the building they are in is a medical laboratory created for him to use.
The lab is covered in medical equipment, ranging from scalpel to test-tubes. The lab's most unique feature, however, is the large blood extracting machine in the center of the room. One of the room's massive walls is covered in ceiling length shelves stacked full of jared animals, books, scrolls, crates, and tools. Kabuto later comes here to transfuse blood of Orochimaru's true form into himself. In the background, several tanks contain large snake-like entities. One of them had an upper body that looked human. Several years later, the same tanks are noticeably empty.