Kame House (lit. "Turtle House") is a house on a very small island in the middle of the sea. It is the home of Master Roshi, and for much of the Dragon Ball Series, Launch as well. It also becomes Krillin's permanent residence. During the Majin Buu Saga, we see that he still lives here along with his wife and daughter.

The house itself is very distinctive. It is painted pink, with a red roof, and the words "KAME HOUSE" are displayed prominently on the front of the upper story.

Kame House is the primary training site of Goku, Krillin, and later Yamcha during the Tournament and Fortuneteller Baba Sagas. During the Dragon Ball anime, it served as a de facto stronghold for the Z-Fighters, but during Dragon Ball Z, the team used Kami's Lookout as their base of operations instead, using the house primarily as a hideout due to its location.