I think you did each feature well, but they don't line up with each other. This makes the face look twisted. In general, your features should be parallel with each other. I did some quick doodles to show you what I mean:
The nose and the mouth have the most different axis on your drawing, but the other features are slightly off too.
We are used to looking at human faces, so when a drawing is a little off, it tends to get noticed. My advice would be to do a quick check during your sketching phase to make sure that the features are correct relative to each other.
That being said, I think the rest of the picture is very good. You have very good control over your colored pencils. The shading and colors are really nice.
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