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Onion Extract acts as an anti-inflammatory and seems to inhibit the over-production of collagen in a scar. Onion extract is available in the United States as a gel by itself, but is also an ingredient in Mederma gel, a widely used scar treatment that you referred to in your question. Onion extract, by itself or as part of another course of treatment, requires consistent use over several months in order to produce any effect.

Silicone, available either as a gel or in rubber-like sheets, has been found to lighten and flatten scars. You apply the gel directly to the scar or use medical tape to cover the scar with the silicone sheet. It isn't known exactly how silicone helps scars heal — some researchers think that static electricity from the silicone helps align collagen fibers in the scar, while others think it might help trap moisture, which can help make scars fade.

Alpha Hydroxy Acids are natural fruit acids that are used to exfoliate (remove) dead skin cells. This process can improve the appearance of scars and reduce redness, as well as wrinkles and signs of aging. If you decide to use alpha hydroxy, investigate the various strengths and use the mildest. For people with sensitive skin, alpha hydroxy can cause irritation, stinging, and other problems. A health care provider or dermatologist can advise you on which types and concentrations of alpha hydroxy acids you can try.

Retinoid or Retinal: A topical Retinoid requires a prescription but Retinals are available over-the-counter. Both are helpful for regenerating the skin and fading scars

Vitamins and minerals: Don’t underestimate the importance that well-nourished, healthy skin plays in the way scars heal.

Dermabrasion or microdermabrasion
Either technique can be used to minimize small irregularities like surgical scars or acne scars. It involves removing the surface layers of the skin with an electrical implement that abrades the skin, resulting in smoother skin. Note that dermabrasion is a more invasive procedure and is only performed by a medical doctor. Microdermabrasion can have a similar effect, but requires a series of treatments to be effective. A trained esthetician or a dermatologist can perform microdermabrasion.

Chemical peels
The peels used to treat superficial facial scarring remove the top layer of the skin, causing it to regenerate and eventually take on a more uniform appearance. The most common chemical peels are TCA peels and glycolic glycolic peels. Depending upon the strength of the chemical solution, peels might need to be repopulated to see results. For serious scarring, chemical peels should be performed under medical supervision.

Injections
Injectable fillers are an option for plumping up sunken scars. The most common fillers for scarring are collagen (derived from purified bovine collagen) and restylin (derived from hyaluronic acid). Injections are temporary and must be performed by a board-certified physician.

Laser resurfacing
This method refers to C02 and Erbium Yag lasers used to remove the skin’s surface layer(s) and burn off damaged skin. In addition to minimizing fine scars, lasers can lessen the look of wrinkles.