Alchemising with the Alchemiter can be fun, but make sure you keep it simple. Some objects that are OP for your level should be too hard to obtain due to the grist you need.

We can sort them into several levels:

Trivial: Only requires 1-3 Grist to make it, almost simple in use, if any. No knowledge or training necessary.
Easy: Requires more Grist than Trivial. Strife Specubi items may be alchemised at this level. Not as simple to find a purpose for the object, or to use it, but barely. Slight training needed.
Normal: Requires two different types of Grist, and more than before. Strife Specubi items are more powerful and may have one special effect. Objects more defined, have more practical use or value or just seem to make no sense until later. Some training will be necessary for these.
Difficult: Requires three or more types of Grist, or a whole lot of one type. Strife Specubi items more powerful than Normal, will always have 1 effect. Object's purpose is clear, use isn't hard to find, but power makes it harder to master than others.
Nigh but Impossible: Requires all the types of Grist, or so many of one or two types you could build a 100 story building with it all, rooms included. The Strife Specubi items here are some of the best, and comes with the added benefit of either 2 effects or one strong effect. Object is harder to use with more power, and may even require God tier to ensure maximum proper use.
One of a Kind: Requires unknown amounts of Grist. These items can only be found as loot whilst exploring your Land in the Incipisphere. These items are like myths to their inhabitants, but may just seem like a legendary piece of sh*t to your character. These objects tends to have the strongest abilities.

Feel free to note down any combinations your character comes across down below.