About

It begins in The Hive, a top-secret genetic research facility owned by the Umbrella Corporation located deep beneath Raccoon City. A technician loads vials of blue and green liquid into a secured case, then tosses one blue vial onto the floor inside a lab, exits and seals the room. The vial breaks and the facility's security system, the Red Queen detects possible infection, and in response, seals the Hive and kills everyone inside.

Elsewhere, a woman known only as "Alice" awakens in an empty mansion with amnesia. She finds a picture showing that she is married; other clues, like concealed automatic weapons, suggest she is not a simple housewife. After she steps outside the mansion door, a man yanks her back inside; the two are immediately seized by a group of commandos. The man, Matthew Addison, identifies himself as a police officer, but the commandos handcuff him regardless. The team opens a mirror-door to an underground train station. While taking a route to the Hive underground train station, the team discovers an unconscious man, known as Spence. Alice recognizes him as the man in the wedding photograph. Questioning reveals that he also suffers from amnesia. When the train arrives at the Hive, the commandos prepare to breach the Hive.

The "One", as he is called, is the head of the commandos and explains that Alice, Spence, and the commandos, are employees of the Umbrella Corporation, and it was Umbrella that sent the team to investigate why the Red Queen killed all the Hive staff. The computer has characteristics of a person, such as a gender. She is responsible for releasing a nerve gas in the mansion which has caused Alice and Spence's amnesia. The crew find their way to the Dining Hall B up to the Queen's chamber. However, as the bulk of the team attempt to disable the Red Queen, four of them are trapped in the corridor leading to the Queen's Chamber and are torn apart by a laser tripped when the Queen's door was opened. This leaves Alice , Spence, Kaplan, J.D., Rain and Matt as the only survivors. Alice and Kaplan shut the Queen down, but in doing so open the doors of the facility, releasing the undead staff and experiments from the laboratories in which they were imprisoned. A battle between commandos and flesh-eating zombies commences. Rain becomes infected after receiving multiple bite wounds, and a battle ensues in which Matt and Alice are separated and J.D. is eaten alive by zombies. Kaplan, Rain and Spence remain in the control room in front of Red Queen's chamber. When Alice and Matt were together in another facility of the Hive, they talked together and Alice discovers that Matt was not a police officer, and used the title as a cover in his goal to help take down the Umbrella Corporation. Matt, with the help of his sister, Lisa, unsuccessfully attempts to smuggle a sample of the T-Virus, the cause of the undead. Matt believes this to be the fault of Lisa's contact, who supposedly betrayed her. Throughout the film Alice has flashbacks, showing herself as Lisa's contact, but Alice is not fully aware of her role in the events.


Milla Jovovich as the protagonist, AliceSoon, the survivors are once more united at the Queen's chamber and are forced to switch her back on for aid in an exit. Kaplan overrides the Queen's circuit-breaker, causing the next time she is disabled to be permanent, and the Red Queen somewhat agrees to aid the team. As Alice and the others try to escape through the maintenance tunnels, they are ambushed by zombies. Rain becomes severely injured and begins to weaken, while Kaplan is separated from the rest of the team and is assumed dead. On their way to the train, Alice remembers that an anti-virus exists that could cure infection. However, arriving at the lab, they realize that the vials containing the T-Virus and anti-virus are gone. Spence, gaining his memory, is then shown as the person who released the virus. He points a gun at the survivors, and threatens them, trapping the others in the laboratory and making for the train where the case containing the anti-virus is. Before he can inject himself, however, he is killed by a mutated creature from a breed, called the Licker. The Queen offers to spare Alice and Matt's life if they kill Rain, who has been infected for the longest period of time. As the Licker attempts to bash through the lab window to get to them, Alice smashes the Queen's monitor, and there is suddenly a power-outage. The laboratory door opens to reveal Kaplan, who has permanently disabled the Red Queen.


A newspaper headline displaying: The Dead Walk! as an homage to George A. Romero's Day of the Dead.The four survivors hurry to get to the other end of the railway before it shuts down in a quarantine attempt. However, the Licker is on the train; it scratches Matt and kills Kaplan. Alice does battle with the Licker while Matt kills Rain who has turned into a zombie. Matt opens the trap door the Licker is standing on. The Licker is dragged along the track and burned to death. Matt and Alice emerge as the only survivors, and escape at the last moment when the doors close. Matt begins to suffer a mutation from an injury inflicted by the Licker, and the two are seized by Umbrella scientists. The scientists sent Matt into the "Nemesis Program". Alice attempts to fend off the scientists, but is ultimately subdued. As the struggle fades to black, the words of one of scientists are heard, "We're reopening the Hive. I want to know what really went on down there. Just do it." Later, Alice awakens at the Raccoon City Hospital and locked in an observation room. After escaping the room and wandering the hospital's empty halls, Alice exits the building to find Raccoon City abandoned with signs of chaos everywhere. Alice takes a shotgun from a nearby police car, anticipating the danger ahead.