I always assign ringsets to structure crews around how I tank.
I have several variations of a build for YM
Diagnose, Bandage, Wish, Meat, Iron Will, Hot Foot, Integ, fitness
If I have a lot of low levels and am concerned about how well I can heal some if they make unwise positioning choices when they attack I'll change my set to increase my dodge so I spend less time healing myself and more on others if they need it.
Diagnose, Bandage, Wish, Meat, Buff, Fortune's favor, Integ, Fitness
If I want to increase the speed of the run by giving my DPSers more attacks I'll take more buffs.
Diagnose, Bandage, Wish, Meat, Buff, Buff, Integ, (fitness or buff)
If I want to help clear the room but push myself on how much I can heal.
Diagnose, Bandage, Wish, Meat, Buff, Hack, Mantis, Integ
I think tanking YM without wish is a foolish thing to do because it limits how much you can heal a group and limits how much aggro you can hold when it gets stolen inevitably. It also requires you to stand much closer to the crew.
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For Green Rooms through HPR I use two sets
My preferred is
Diagnose, Bandage, Meat, Integ, Keen Aye, Quicksand, Shark Attack, Slash
Keen is not a vital buff and it does scale and is not rageable so that's good for a healer to have. The armor bonus makes most rooms a breeze and I can tank just like Yellows though healing the crew is much more difficult.
If I run into a room with 4-5 packs of bats I might switch out my set to one that gives me some invulnerability and higher dodge and the ability to run faster.
Diagnose, Bandage, Meat, Turtle, Integ, Quicksand, Sugar Rush, Keen aye
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Once I hit Crypt I change my ring set out to
Diagnose, Bandage, Wish, Meat, Hack, Integ, (fitness or slash), Keen
Basically my YM set. If I feel like two attacks I carry slash because it helps with bats swarms. I also need wish if I'm to tank 10+ enemies on screen at a time without anyone using crowd control. I also can help with coffin spawns more with high dps melee rings than a ranged ring like I used to tank with.
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For Bloodlust my set depends on how competent I think my backup healer is and if someone in crew has Sweetheart
If nobody has Sweetheart I have to tank it
Diagnose, Bandage, Turtle, Meat, Sweetheart, Integ, Fitness, Sugar Rush
If someone does then I take an attack. I take Hot foot because it has a good AoE at r4 and it debuffs dodge on bats. The downside is the lower dps of the ring means I lose aggro to someone sooner in the run.
Diagnose, Bandage, Turtle, Meat, Hot foot, Integ, Fitness, Sugar Rush
If I think my backup healer is going to do a fantastic job I can drop turtle. They have to be really good at multi-tasking because turtle is a safety net against Bat attacks if the bats reach me.
Diagnose, Bandage, Meat, Shuriken, Hot foot, Integ, Fitness, Sugar Rush.
The DPS of the two combined rings means I rarely lose aggro to the crew and I do a respectable amount of damage to Kamila too. It's an expensive way to tank, however, because I use more superchargers for stamina. Gets the run fast though if everything goes well.
I don't assign knife for Bloodlust so my backup healer really as to know what they're doing.