Creativerealms
They are still i like every episode of the show the same as they always were.
As for Misty being replaced, best thing that ever happened. I like Misty I really do but it was no fair that characters from the first game kept being main characters while characters from the later games were treated like crap.
Replacing Misty with May and later Dawn was the best thing they could do. It showed respect to the later games. And As for Misty she is currently a Gym leader and still shows up from time to time so they still treat her with respect.
But what about the male heroes from the later games? Sadly they keep getting screwed over whhile Red (Ash) continues to be the main character. Ash should have left when the Red/Green/Blue/Yellow story ended. Where is the hero from the Advance games? Where is the hero from the DS games? While are they screwed over for Ash? Thats no fair.
While I don't like Ash without Misty and Brock, unless Tracey's around - they do touch on Gold in the Chronicles as well, so there is some respect given. They can't take away Ash, as he's the main character, so the best they do is change the team up occasionally.
I personally would prefer a whole side series, focusing on a different group of trainers, and having them occasionally run into Ash and his group or something while they, too, strive to be the best trainers. Especially since that would make the voice cast issue go away. XD But that would never happen.