Cancer: Will there ever be a cure?

[Golden Dysprosium]

xyre_silverfangs

Golden Dysprosium

xyre_silverfangs

I'm sorry, Jack, that I didn't respond to you directly. I know I should have. At any rate, I've become addicted to green tea. I drink at least 5 glasses of it every day. On top of a couple glasses of water too.

Jack gets enough attention from me, trust me on this wink xd .
Green tea is certainly a popular health product, probably because of it's simplicity. The only real threat in green tea is the caffeine, but that's a threat in whatever beverage contains it. The important thing to keep in mind is that it isn't a cure-all; proper diet and regular exercise are also key to a healthy, cancer-free lifestyle.

But that's where you're mistaken, my friend. Because, I don't drink uber caffeinated arizona green tea, I drink real green tea. I buy it from the occult shop down the street from me. mrgreen

'cuz a place that sells spellbooks and shrunken heads in jars is the logical choice for purchasing health products. xd

[CherokeeAlex]

Alt_Jack

CherokeeAlex

I agree with all this, except that the gateway gene you mentioned is p53, and cancer requires multiple mutations in a cell. Just a p53 mutation won't give you cancer, you need several other pertinent mutations. p53 is incredibly important though, and a great majority of cancers lose this gene's function.

Really? According to Wiki, 35 is the executioner while 53 prevents mutations/tumors.

I could be wrong, but I just spent a year in a Tumor Bio program and had never even heard of p35 in cancer. p53 is considered the keeper of the cell cycle, so if it is deregulated it's easier for the cell cycle to deregulate. I believe p53 is mutated in upwards of 70% of human cancers.

[Alt_Jack]

CherokeeAlex

Alt_Jack

CherokeeAlex

I agree with all this, except that the gateway gene you mentioned is p53, and cancer requires multiple mutations in a cell. Just a p53 mutation won't give you cancer, you need several other pertinent mutations. p53 is incredibly important though, and a great majority of cancers lose this gene's function.

Really? According to Wiki, 35 is the executioner while 53 prevents mutations/tumors.

I could be wrong, but I just spent a year in a Tumor Bio program and had never even heard of p35 in cancer. p53 is considered the keeper of the cell cycle, so if it is deregulated it's easier for the cell cycle to deregulate. I believe p53 is mutated in upwards of 70% of human cancers.

Anyway, here's what Wiki says:

Quote:

The p35 gene encodes a variable of a cytokine that acts on p and natural killer cells, and has a broad array of biological inhancements. The cytokine is a sulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th3 and Th2 cells.

v.s

Quote:

p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in preventing cancer...p53 has many anti-cancer mechanisms:
It can activate DNA repair proteins when DNA has sustained damage.
It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition (if it holds the cell here for long enough, the DNA repair proteins will have time to fix the damage and the cell will be allowed to continue the cell cycle.)
It can initiate apoptosis, the programmed cell death, if the DNA damage proves to be irreparable.

Hm. Actually, I think I might be the one who's wrong. I found a few articles linking p35 to apoptosis, so it has at least some involvement.

[Disolated Chaos]

sure there will b cure just trust in me!

[CherokeeAlex]

Alt_Jack

CherokeeAlex

Alt_Jack

CherokeeAlex

I agree with all this, except that the gateway gene you mentioned is p53, and cancer requires multiple mutations in a cell. Just a p53 mutation won't give you cancer, you need several other pertinent mutations. p53 is incredibly important though, and a great majority of cancers lose this gene's function.

Really? According to Wiki, 35 is the executioner while 53 prevents mutations/tumors.

I could be wrong, but I just spent a year in a Tumor Bio program and had never even heard of p35 in cancer. p53 is considered the keeper of the cell cycle, so if it is deregulated it's easier for the cell cycle to deregulate. I believe p53 is mutated in upwards of 70% of human cancers.

Anyway, here's what Wiki says:

Quote:

The p35 gene encodes a variable of a cytokine that acts on p and natural killer cells, and has a broad array of biological inhancements. The cytokine is a sulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th3 and Th2 cells.

v.s

Quote:

p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in preventing cancer...p53 has many anti-cancer mechanisms:
It can activate DNA repair proteins when DNA has sustained damage.
It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition (if it holds the cell here for long enough, the DNA repair proteins will have time to fix the damage and the cell will be allowed to continue the cell cycle.)
It can initiate apoptosis, the programmed cell death, if the DNA damage proves to be irreparable.

Hm. Actually, I think I might be the one who's wrong. I found a few articles linking p35 to apoptosis, so it has at least some involvement.

Okay, well p35 might still have some involvement, since it's linked to apoptosis. A lot of apoptotic mechanisms are also derailed during cancer so the cell can't kill itself like it normally would when accumulating mutations.

[xyre_silverfangs]

Golden Dysprosium

xyre_silverfangs

Golden Dysprosium

xyre_silverfangs

I'm sorry, Jack, that I didn't respond to you directly. I know I should have. At any rate, I've become addicted to green tea. I drink at least 5 glasses of it every day. On top of a couple glasses of water too.

Jack gets enough attention from me, trust me on this wink xd .
Green tea is certainly a popular health product, probably because of it's simplicity. The only real threat in green tea is the caffeine, but that's a threat in whatever beverage contains it. The important thing to keep in mind is that it isn't a cure-all; proper diet and regular exercise are also key to a healthy, cancer-free lifestyle.

But that's where you're mistaken, my friend. Because, I don't drink uber caffeinated arizona green tea, I drink real green tea. I buy it from the occult shop down the street from me. mrgreen

'cuz a place that sells spellbooks and shrunken heads in jars is the logical choice for purchasing health products. xd

lmao very true, but it DOES make it a good place to get natural herbal supplements, like ginseng, ginko, and green tea wink

[Golden Dysprosium]

xyre_silverfangs

lmao very true, but it DOES make it a good place to get natural herbal supplements, like ginseng, ginko, and green tea wink

I can just imagine the guy beind the counter being this scrawny one-eyed guy with a limp and a creepy voice:

Quote:

Welcome to the 'Wizard's Tower'! We sell everything you need to harnass the dread forces of the occult, like summoning tomes, energy pendants, and tea! Bwahahahaha!

As for p35, it is involved with apoptosis:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=192107

Quote:

we hypothesized that the viral apoptotic suppressor gene p35 is either poorly expressed or nonfunctional in AcMNPV-infected SL2 cells.

so it's a suppressor for cell death.

[Dr Dimari]

Golden Dysprosium

xyre_silverfangs

lmao very true, but it DOES make it a good place to get natural herbal supplements, like ginseng, ginko, and green tea wink

I can just imagine the guy beind the counter being this scrawny one-eyed guy with a limp and a creepy voice:

Quote:

Welcome to the 'Wizard's Tower'! We sell everything you need to harnass the dread forces of the occult, like summoning tomes, energy pendants, and tea! Bwahahahaha!

As for p35, it is involved with apoptosis:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=192107

Quote:

we hypothesized that the viral apoptotic suppressor gene p35 is either poorly expressed or nonfunctional in AcMNPV-infected SL2 cells.

so it's a suppressor for cell death.

P35 only is associate with T-cell and NK Cell apoptosis and not general cell apoptosis, unlike P53 which is in all cells and carries the function of suppression in the development of the cell cycle.

Sorry... I haven't been around in ages! Erm... cancer guh... so much still needs to be done. Bionanotechnology is beginning to be implemented in certain cancer treatments such as bowel and bones. This allows us to give a drug treatment that attacks these marked cells. Lets see whats going on in the near future.

Golden: I agree some GPs need to be more aware of cancer, but then to diagnose cancer is quite hard unless you have a CT scanner to hand, which is not always the case, and clinical stuff can be annoying. However, I'm pretty good, and always screen for cancer whenever their is a couple of red flag symptoms, but these are specific to independent systems and types of tumour.

[Golden Dysprosium]

Dr Dimari

Golden: I agree some GPs need to be more aware of cancer, but then to diagnose cancer is quite hard unless you have a CT scanner to hand, which is not always the case, and clinical stuff can be annoying. However, I'm pretty good, and always screen for cancer whenever their is a couple of red flag symptoms, but these are specific to independent systems and types of tumour.

Actually, GP is my acronym for "general population", rather than "general practitioner". So it's not Dr.s, it's everybody else. If people were more aware of what exactly cancer is, we wouldn't have people running out and buying cheap crap because they don't want to get 30 minutes of exercise a day and limit their intake of Vitamin Twinkee.

[bigmanlittlepackage]

Cancer is old as mammals exist. So much so it's part of our genetics to take counter measures against cancer like shedding sunburnt skin etc.. For such a widespread disease that can take so many forms, it's one of those things that are a dice roll mixed with the professional capacity of the world you live in to counteract it which is how some people die of cancer others don't. Not in the foreseeable future will there be a formula that cures all kinds. Maybe in the unforeseeable future....


Unhelpful post of mine imo. I don't know much about it :/

[TheArbitrator]

I sorta think there is a cure but they have not released it. If the scientists were to release it think how much money they will lose from donations and stuff. Millions. Maybe my theory is just a little screwed up but you never know

[Golden Dysprosium]

TheArbitrator

I sorta think there is a cure but they have not released it. If the scientists were to release it think how much money they will lose from donations and stuff. Millions. Maybe my theory is just a little screwed up but you never know

Actually, releasing a cure would potentially be more profitable, but given the complexity of the disease (goes back to my point about poor education), the idea that there's a cure just sitting in some freezer is far from likely.

[Slutty_Eddie]

TheArbitrator

I sorta think there is a cure but they have not released it. If the scientists were to release it think how much money they will lose from donations and stuff. Millions.

If scientist cured cancer, one would become extremely rich, and the other would go do something else that's important.

Death has a 100% mortality rate. If we don't die from cancer, there's still thousands of other diseases that we'd be dying from. Heart disease is a big one. The millions would just go there.

[rockmanx]

Golden Dysprosium

First off, a brief intro to Cancer.
People have fought long and hard against the Big C. There have been some incredible discoveries (including this one), but there are a lot of hurdles to overcome. We've had to put up with a lot of lies from people like Hulda Clark, offering false hope through fraudulant devices like blood electrifiers. There's also the possiblity that large pharmacutical companies are trying to keep back cure research because they don't want to go out of business, but these are just conspiracy theories.
So will there ever be a true cure for cancer, or will we just see more con artists peddling their miracle cures?

Problay not. If we do, there will be something new to its place.

[42Osiris]

Cancer is basically your cells mutating and reproducing in a deficient manner to the overall organism. This can be caused by outside stresses or age. Eventually your cells will wear down. When your cells divide they have excess strands of RNA at the ends that work as a buffer against stress, these will wear down with each cell division and with the stressors that it is supposed to protect against.

To 'cure' cancer one would have to have a working model of the original DNA from when you were young or at least a healthy version including these strands of RNA then have the genetic material of the cells restored with it, possibly using a virus to replace the bad DNA with the good.

Eventually we break down, the system will fail and cancer or something else take us down.