Hantei
Meh, no big loss to me. I personally thought that his story was finished with 3, besides his appearance in 4 wouldn't equate to us playing as him anyway. Also, just because Kobayashi said no Vergil doesn't mean there might not be Nelo Angelo. So hey, even though it's very unlikely, Nelo could make it into the game.
From the lies we've been presented with from the start of the development of DMC4 I'm guessing that Vergil's either going to be in it for sure or they're saying "Oh, VERGIL doesn't come in...
but Nelo Angelo does <.< >.> *sniggers at how wonderfully clever he's being*"
And Kinky, post my reply to your PM here. I feel it fits this very well.
To be honest though, Vergil not being in it doesn't kill me too much. If he's not a playable bonus character it'd piss me off. Nelo being in it but no sight of Vergil in human form would also grind my gears (yay! I finally used that term!) because Nelo's nowhere near as interesting as Vergil. Then again, if he gets a DMC3 style makeover for DMC4 he'd probably be a snuggle worthy character.