Really depends on your taste. Mine are a bit, off, but I do have some suggestions.
Spider-Man 2099 by Peter David, old and current. SM2099 is hilarious. Miguel is a lovable a*****e. Peter David is high on snark and it really shows through Miguel's attitude. After PD got off the book, it went into a sharp decline. If you like Peter Parker, maybe skip this and the next two.
Scarlet Spider by Chris Yost. Kaine is cured of his celluar degeneration and now has a chance to live his life. Unfortunately, after robbing smugglers in Texas, Kaine becomes the protector of Houston and a girl, Aracely, who is possessed by an Aztec God. Kaine is capable of humor, more through dry, ruthless shouts and thoughts. It definitely put a lot of faith into Yost for me as I hated Kaine since Ben died.
The Superior Spider-Man by Dan Slott. I loved this series to death. It's not only a joy as the misadventure of Dr. Octopus in Peter's body escalates with each episode, but it is filled with a ton of meta. The genre was flipped on its head in a ballsy, but necessary move. Love it or love to hate it, your choice.
Thanos: Infinity Revelations by Jim Starlin. If you like Thanos but never heard of Starlin, you've been doing it wrong. Starlin is back to reclaim Thanos and Adam Warlock in his mind-bending, universal drama that simultaneously takes place between two universe to very different degrees. Its really Starlin's way of questioning the reader if they are ok with vary levels of misinterpretation and the state of the comic industry. A good chunk of it is the annoyance of Starlin and how people have handled Thanos and Warlock while he was gone.
The Infinity Gauntlet by Jim Starlin. This is the epic crossover in which Thanos amped up his game to please death and ultimately validate himself. The Avengers weren't avenged, the X-men Xterminated, and the only thing standing between Thanos and complete universal destruction is Adam Warlock and what's left of the Defenders.
Death of Captain Marvel by Jim Starlin. At this point you can see that I like Starlin. As it stands, Starlin is the grandfather of cosmic Marvel, paving the way for the others that would follow. Mar-Vell is a fascinating character largely by his role as a person. A former Kree solider, Mar-Vell was stationed on earth to see if it can be used as an outpost in the war. Mar-Vell fell in love with earth and stood against his people and was later known as Mar-Vell. Despite gaining cosmic awareness, he ultimately succumbed to a foe none have yet to beat, cancer. Death of Captain Marvel follows a few pivotal chapters in his life, like gaining cosmic awareness and the fight that would lead to his death, It's a bitter book regarding the slow decay of Mar-Vell as his ability to cope with his declining mortality. It shows how the hero community and those close to Mar-Vell are affected by the very real threat and the futility of fighting something too far along to stop. Jim Starlin had lost his father to cancer at this time and much of his bitterness and feelings of helplessness pull heartstrings as he dumps his feelings out through characters like Spider-Man and Rick Jones.
The Mighty Thorcules by Greg Pak. Zeus is now a child, but some things never change. The damaged dynamic of Herc and Zeus reach a high as Balder the Brave sends Herc to stop the new Dark Elf Queen, only for things to wildly get out of control. To infiltrate the nine realms, Herc pretends to be Thor, in which the Dark Elf Queen thinks he's sexy, Herc's charm pays off and they sleep together. Then, as the dark elves are looking to crush midgard for "thor" Thor appears impersonating Herc.
The Incredible Hercules: Love and War by Greg Pak. Amadeus Cho, Herc's sidekick is kidnapped by Amazons, and while Herc encouraged Cho to get it on with "totally not evil Wonder Woman," as expect from Pak and Herc, things go wildly out-of-control.
I have a ton more but this is a good start.